The mean fat-fraction in healthy patients was around 5%, with less than 2% intra-muscle variability. Whole body MRI was performed on 31 patients, 23 with congenital myopathies and 8 healthy controls, aged between 10 months and 35 years old, from January 2014 to June 2016. The objective of this study was to evaluate the variability in fat quantification using Dixon's technique in a cohort of patients with congenital myopathies, by analysing intra-segment, intra-muscle, and inter-muscle variability of 60 muscles in each patient. There are few reports concerning measurement standardisation with Dixon technique. The Dixon fat-water separation technique allows objective intra-muscular fat quantification. Muscle MRI has emerged as a valuable tool in the diagnosis of neuromuscular-disorders. El estudio permite concluir que existe una alta variabilidad intra e intermuscular en pacientes miopáticos, que no se observa en pacientes sanos. En pacientes con miopatías congénitas existe una variabilidad entre el 3,1-7,8%. En pacientes sanos se estimó una fracción grasa promedio cercana al 5%, con una variabilidad intramuscular inferior al 2%. Se realizó RM de cuerpo completo a 31 pacientes: 23 con miopatía congénita y 8 controles, entre 10 meses y 35 años de edad, desde enero del 2014 a junio del 2016. El objetivo de este estudio fue evaluar la variabilidad en la determinación de fracción grasa utilizando la técnica de Dixon, estudiando la variabilidad intrasegmentaria, intramuscular e intermuscular en 60 músculos por paciente. La técnica de Dixon permite objetivar la fracción grasa muscular, pero no existe consenso sobre la estandarización de estas mediciones. Afghanistan, Algeria, American Samoa, Angola, Anguilla, Armenia, Azerbaijan Republic, Bahamas, Bangladesh, Barbados, Belarus, Benin, Bermuda, Bhutan, Bolivia, Botswana, Burkina Faso, Burundi, Cambodia, Cameroon, Cape Verde Islands, Cayman Islands, Central African Republic, Chad, Comoros, Congo, Democratic Republic of the, Congo, Republic of the, Costa Rica, Cuba, Republic of, Côte d'Ivoire (Ivory Coast), Djibouti, Dominica, Dominican Republic, Ecuador, Egypt, El Salvador, Equatorial Guinea, Eritrea, Ethiopia, Falkland Islands (Islas Malvinas), French Guiana, Gabon Republic, Gambia, Georgia, Ghana, Guatemala, Guernsey, Guinea, Guinea-Bissau, Guyana, Haiti, Honduras, India, Indonesia, Iraq, Jamaica, Jersey, Kazakhstan, Kenya, Kiribati, Korea, North, Kyrgyzstan, Laos, Lebanon, Lesotho, Liberia, Libya, Macedonia, Madagascar, Malawi, Maldives, Mali, Marshall Islands, Mauritania, Mauritius, Mayotte, Moldova, Mongolia, Morocco, Mozambique, Namibia, Nauru, Nepal, Nicaragua, Niger, Nigeria, Pakistan, Palau, Paraguay, Peru, Philippines, Reunion, Russian Federation, Rwanda, Saint Helena, Saint Pierre and Miquelon, San Marino, Senegal, Seychelles, Sierra Leone, Somalia, Sudan, Suriname, Svalbard and Jan Mayen, Swaziland, Syria, Tajikistan, Tanzania, Togo, Trinidad and Tobago, Tunisia, Turkmenistan, Tuvalu, Uganda, United Kingdom, United States, Uruguay, Uzbekistan, Venezuela, Vietnam, Virgin Islands (U.S.La resonancia magnética muscular ha emergido como una valiosa herramienta de apoyo diagnóstico en enfermedades neuromusculares.
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